IJAIR NAAS Score : 3.99 ,ISSN : 2319-1473
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 15, Issue 1, July - Aug., 2026"
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IJAIR NAAS Score : 3.99 (2016 - 2020)
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Journals Published by TimeLine Publication Pvt. Ltd.
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IJAIM , IJRAS , IJISM ,
IJIRES , IJASM , IJRIES,IJAHVS
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 15, Issue 1, July - Aug., 2026"
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IJAIR NAAS Score : 3.99 (2016 - 2020)
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Journals Published by TimeLine Publication Pvt. Ltd.
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IJAIM , IJRAS , IJISM ,
IJIRES , IJASM , IJRIES,IJAHVS
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Submissions open
IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 15, Issue 1, July - Aug., 2026"
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IJAIR NAAS Score : 3.99 (2016 - 2020)
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Effect of Codonopsis pilosula on Expression of Two Different Complement Component 3 in the Sea Cucumber (Apostichopus naponicus)
- Ying Fan; Le Li; Xiaoqing Yu; La Xu; Shuxian Wang; Chunlei Gai; Jing Diao; Xiaolu Wang; Haibin Ye; Danping Ma
- The complement system has been discovered and studied in different tissues of sea cucumber, which play a crucial role in the innate defense. As a central component in the complement system, complement component 3 (C3) is an intermediary between innate and adaptive immune system. In the present study, Codonopsis pilosula (C. pilosula) with the form of microcapsule was supplemented at 1%, 2%, 4% rate of Sargassum thunbergii diet. There was no C. pilosula in the control group. Two C3 genes (AjC3 and AjC3-2) were expressed in the coelomocytes and intestine of sea cucumbers fed with C. pilosula. The expression levels were increased significantly on the 28th day after feeding 2% C. pilosula (P0.05). Moreover the patterns of AjC3 and AjC3-2 were similar, there were significant correlations between the two. The expression levels of them were high in the coelomocytes, lower in the intestine. After feeding for 28 days, ten sea cucumbers from each group were challenged with V. splendidus. Cumulative mortality of sea cucumbers fed with C. pilosula were found to be lower than the control, especially 2% group. The results indicated that AjC3 and AjC3-2 genes played a pivotal role in immune response. C. pilosula could promote the expression of C3, enhance the immune of sea cucumber.
- Select Volume / Issue:
- Year:
- 2020
- Type of Publication:
- Article
- Keywords:
- Codonopsis pilosula; Apostichopus naponicus; Immunity; Complement Component 3; AjC3
- Journal:
- IJAIR
- Volume:
- 8
- Number:
- 4
- Pages:
- 290-299
- Month:
- January
- ISSN:
- 2319-1473
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