IJAIR NAAS Score : 3.99 ,ISSN : 2319-1473

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IJAIR NAAS Score : 3.99 (2016 - 2020)
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 13,Issue 2, Sept. - Oct., 2024"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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"Submissions Open For Vol. 13,Issue 2, Sept. - Oct., 2024"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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IJAIM , IJRAS , IJISM ,
IJIRES , IJASM , IJRIES,IJAHVS
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 13,Issue 2, Sept. - Oct., 2024"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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Acetylcholinesterase Activity in the Brain Regions of Pubertal Pigs Fed Dietary Neem (Azadirachta indica A. Juss) Kernel

Olujide Adedamola Sokunbi; Jovi Richard Otite; John Olusoji Abiola; Olufemi Alaba
Neem kernel (NK) with a higher dietary energy than maize could be a viable ingredient in swine nutrition. However, there are established documentation of many chemical constituents in neem that are classified as antinutrients. Hence, the effects of dietary NK on acetylcholinesterase (AChE) activities in the brain regions of pubertal boars and pigs were investigated. Acetylcholinesterase is the enzyme which catalyses the hydrolysis of acetylcholine and is known to mediate food and water intake. A feeding trial was conducted with forty growing pigs consisting of twenty males and twenty females (8 to 10 weeks old) in a completely randomised design, to evaluate the influence of NK inclusion in swine diets at 0, 50, 100 and 150 g/kg, on AChE activities in the brain regions of pigs. The pigs were raised until they attained pubertal age and were subsequently sacrificed. The AChE activity (µmole/g/minute) was determined by colorimetric method. Data were analysed using descriptive statistics and ANOVA at α 0.05 Pigs on 150 g/kg NK diet showed significantly (P0.05) reduced AChE activities in cerebrum, cerebellum, mesencephalon, pons varolii, and medulla oblongata compared to those on control. Significant (P0.05) increase in AChE activity was, however, observed for hypothalamus. Neem kernel can be included up to 100 g/kg in swine diets without deleterious effects on the AChE activities in the brain regions of growing pigs. Also, results suggested that effects of NK on AChE activities were more pronounced in pubertal gilts than in boars.
Select Volume / Issue:
Year:
2024
Type of Publication:
Article
Keywords:
Neem Kernel; Acetylcholinesterase Activity; Brain Regions; Growing and Pubertal Pigs
Journal:
IJAIR
Volume:
12
Number:
5
Pages:
179-189
Month:
March
ISSN:
2319-1473
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